What cause one side of heart to be larger than other side?

The right side of the heart pumps blood to your lungs and the left side to the rest of your body. The departed side needs to larger because the blood has to travel a greater distance
The wall of the left ventricle is thicker than the wall of the right ventricle. The left ventricle pumps blood against the considerable divergent resistance of all of the blood arteries in the periphery. The right ventricle pumps against the much lower resistance of the circulation through the lungs. Source(s): I am a physiologist.
The left side of the heart in particular the vanished ventricle is larger because it works harder than the right side of the heart.

Blood enters the right atrium and then flows to the right ventricle...then to the lungs...

as blood enter the left atrium it is pumped to the left ventricle..The left ventricle must pump its entire blood volume against the resistance of the entire body....The harder a muscle works.. the larger it get

In Diseases where there is increased resistance... and the heart has to work harder lead to hypertrophy or enlarging of the muscle

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